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Article|11 Dec 2023|OPEN
The Botrytis cinerea effector BcXYG1 suppresses immunity in Fragaria vesca by targeting FvBPL4 and FvACD11
Liyao Su1 ,† , Tian Zhang1 ,† , Bin Yang2 ,† , Yibo Bai1 , Wanping Fang2 , Jingsong Xiong1 and Zong-Ming (Max) Cheng,1 ,
1State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Horticulture, Nanjing Agricultural University, Nanjing 210095, China
2College of Horticulture, Nanjing Agricultural University, Nanjing 210095, China
*Corresponding author. E-mail: zmc@njau.edu.cn
†Liyao Su,Tian Zhang and Bin Yang contributed equally to the study.

Horticulture Research 11,
Article number: uhad251 (2024)
doi: https://doi.org/10.1093/hr/uhad251
Views: 86

Received: 10 Sep 2023
Accepted: 14 Nov 2023
Published online: 11 Dec 2023

Abstract

Botrytis cinerea is one of the most destructive pathogens in strawberry cultivation. Successful infection by B. cinerea requires releasing a large number of effectors that interfere with the plant’s immune system. One of the effectors required by B. cinerea for optimal virulence is the secreted protein BcXYG1, which is thought to associate with proteins near the plasma membrane of the host plant to induce necrosis. However, the host proteins that associate with BcXYG1 at the plasma membrane are currently unknown. We found that BcXYG1 binds to FvBPL4 and FvACD11 at the plasma membrane. Both FvBPL4 and FvACD11 are negative regulators of plant immunity in strawberry. Our results demonstrate that degradation of FvBPL4 by BcXYG1 promotes disease resistance while stabilization of FvACD11 by BcXYG1 suppresses the immune response. These findings suggest that BcXYG1 suppresses plant immunity and promotes B. cinerea infection by regulating FvBPL4 and FvACD11 protein levels.